†with Suda as the first affiliation; #co-first authors; *corresponding author

1.    †Cao B#, Li J#, Zhou X, Juan J, Han K, Zhang Z, Kong Y, Wang J, Mao X*. Clioquinol induces pro-death autophagy in leukemia and myeloma cells by disrupting the mTOR signaling pathway. Sci Rep 2014;4:5749.

2.    †Chen G, Han K, Xu X, Du X, Zhang Z, Tang J, Shi M, Wang M, Li J, Cao B, Mao X*. An anti-leishmanial thiadiazine agent induces multiple myeloma cell apoptosis by suppressing the nuclear factor kappaB signaling pathway. Brit J Cancer 2014;110:63-70.

3.    †Chen G#, Xu X#, Tong J, Han K, Zhang Z, Tang J, Li S, Yang C, Li J, Cao B, Zhou H, Wu D, Moran MF, Mao X*. Ubiquitination of the transcription factor c-MAF is mediated by multiple lysine residues. Int J Biochem Cell Biol 2014;57:157-66.

4.    Chen S, Zhu L, Huang J, Cai Y, Lu X, Yang Q, Wu Q, Chen C*, Wang Z*. Arsenic trioxide targets MiR-125b in glioma cells. Curr Pharm Des 2014;20:5354-61.

5.    †Dong N, Zhou T, Zhang Y, Liu M, Li H, Huang X, Liu Z, Wu Y, Fukuda K, Qin J, Wu Q*. Corin mutations K317E and S472G from preeclamptic patients alert zymogen activation and cell surface targeting. J Biol Chem 2014;289:17909-16.

6.    Fan X, Shi P, Dai J, Lu Y, Chen X, Liu X, Zhang K, Wu X, Sun Y, Wang K, Zhu L, Zhang C, Zhang J, Chen G, Zheng J*, Liu J*. Paired immunoglobin-like receptor B regulates platelet activation. Blood 2014;124:2421-30.

7.    †Ge L, Ye F, Mao X, Chen J, Sun A, Zhu X, Qiu H, Jin Z, Miao M, Fu C, Ma X, Chen F, Xue S, Ruan C, Wu D*, Tang X*. Extramedullary relapse of acute leukemia after allogeneic hematopoietic stem cell transplantation: different characteristics between acute myeloid leukemia and acute lymphoblastic leukemia. Biol Blood Marrow Transplant 2014;20:1040-7.

8.    Guo D, Zhao Y, Zhang Y, Wang Q, Huang Z, Ding Q, Guo Z, Zhou X, Zhu L, Gu N*. The cellular uptake and cytotoxic effect of silver nanoparticles on chronic myeloid leukemia cells. J Biomed Nanotechnol 2014;10:669-78.

9.    †Han K, Xu X, Chen G, Zeng Y, Zhu J, Du X, Zhang Z, Cao B, Liu Z, Mao X*. Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization. J Hematol Oncol 2014;7:9.

10.   †Hu C#, Chen Z#, Zhao W, Wei L, Zheng Y, He C, Zeng Y, Yin B*. Vesicular stomatitis virus G glycoprotein and ATRA enhanced bystander killing of chemoresistant leukemic cells by herpes simplex virus thymidine kinase/ganciclovir. Biomol Ther (Seoul) 2014;22:114-21.

11.   †Jiang G#, Ma S#, Wei Y#, Wu Y, Yu X, Liu H*. The prevalence and distribution of Th17 and Tc17 cells in patients with thyroid tumor. Immunol Lett 2014;162:68-73.

12.   †Jiang J#, Yang J#, Feng P#, Zuo B, Dong N, Wu Q*, He Y*. N-glycosylation is required for matriptase-2 autoactivation and ectodomain shedding. J Biol Chem 2014;289:19500-7.

13.   Kimani SG, Geng K, Kasikara C, Kumar S, Sriram G, Wu Y, Birge RB*. Contribution of defective PS recognition and efferocytosis to chronic inflammation and autoimmunity. Front Immunol 2014;5:566.

14.   †Li J, Zhu J, Cao B, Mao X*. The mTOR signaling pathway is an emerging therapeutic target in multiple myeloma. Curr Pharm Des 2014;20:125-35.

15.   †Liang Y#, Ma S#, Zhang Y, Wang Y, Cheng Q, Wu Y, Jin Y, Zheng D, Wu D, Liu H*. IL-1β and TLR4 signaling are involved in the aggravated murine acute graft-versus-host disease caused by delayed bortezomib administration. J Immunol. 2014;192:1277-85.

16.   Liu C, Zhao G, Mao X, Suenaga T, Fujishima T, Zhang C, Liu Z*. Synthesis and biological evaluation of 1α, 25-dihydroxyvitamin D3 analogues with aromatic side chains attached at C-17. Eur J Med Chem 2014;85:569-75.

17.   Liu J#, Wan L#, Liu P#, Inuzuka H, Liu J, Wang Z*, Wei W*. SCFβ-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway. Oncotarget 2014;5:1026-37.

18.   Liu P, Begley M, Michowski W, Inuzuka H, Ginzberg M, Gao D, Tsou P, Gan W, Papa A, Kim BM, Wan L, Singh A, Zhai B, Yuan M, Wang Z, Gygi SP, Lee TH, Lu KP, Toker A, Pandolfi PP, Asara JM, Kirschner MW, Sicinski P, Cantley L, Wei W*. Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus. Nature 2014;508:541-5.

19.   Liu P#, Wang Z#, Wei W*. Phosphorylation of Akt at the C-terminal tail triggers Akt Activation. Cell Cycle 2014;13:2162-4.

20.   †Liu Q#, Chen W#, Jiao Y#, Hou J, Wu Q, Liu Y*, Qi X*. Pulsatilla saponin A, an active molecule from Pulsatilla chinensis, induces cancer cell death and inhibits tumor growth in mouse xenograft models. J Surg Res 2014;188:387-95.

21.   †Liu S#, Wang X#, Li Y, Xu L, Yu X, Ge L, Li J, Zhu Y*, He S*. Necroptosis mediates TNF-induced toxicity of hippocampal neurons. Biomed Res Int 2014;2014:290182.

22.   †Lu J, Zhang W, Yuan L, Ma W, Li X, Lu W, Zhao Y*, Chen G*. One-pot synthesis of porphyrin-glycopolymer conjugate as photosensitizer for targeted cancer imaging and photodynamic therapy. Macromol Biosci 2014;14:340-6.

23.   †Lu W#, Ma W#, Lu J, Li X, Zhao Y*, Chen G*. Microwave-assisted synthesis of glycopolymer-functionalized silver nanoclusters: combining the bioactivity of sugar with the fluorescence and cytotoxicity of silver. Macromol Rapid Commun 2014;35:827-33.

24.   Ma J#, Fang B#, Zeng F#, Pang H, Zhang J, Shi Y, Wu X, Cheng L, Ma C, Xia J*, Wang Z*. Curcumin inhibits cell growth and invasion through up-regulation of miR-7 in pancreatic cancer cells. Toxicol Lett 2014;231:82-91.

25.   †Ma S, Cheng Q, Cai Y, Gong H, Wu Y, Yu X, Shi L, Wu D, Dong C, Liu H*. IL-17A produced by γδ T cells promotes tumor growth in hepatocellular carcinoma. Cancer Res 2014;74:1969-82.

26.   †Meng H#, Zong Y#, Qian J, Jing Y, Tang J, Zou J, An G, Song H, Zhang X, Yang L*. Photothermal targeting therapy of A20 mouse lymphoma model using anti-CD138 antibody-conjugated gold nanospheres. J Hematol Thrombo Dis 2014;2(3).

27.   Nguyen KQ, Tsou WI, Calarese DA, Kimani SG, Singh S, Hsieh S, Liu Y, Lu B, Wu Y, Garforth SJ, Almo SC, Kotenko SV*, Birge RB*. Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity. J Biol Chem 2014;289:25737-49.

28.   †Niu Y#*, Liu Q#, Zhang S, Yuan N, Cao Y, Cai J, Lin W, Xu F, Wang Z, Chen B, Wang J*. Alternative messenger RNA splicing of autophagic gene Beclin 1 in human B-cell acute lymphoblastic leukemia cells. Asian Pac J Cancer Prev 2014;15:2153-8.

29.   †Pan Y#, Meng M#, Zhang G, Han H, Zhou Q*. Oncogenic microRNAs in the genesis of leukemia and lymphoma. Curr Pharm Des 2014;20:5260-7.

30.   †Shang B#, Gao A#, Pan Y#, Zhang G, Tu J, Zhou Y, Yang P, Cao Z, Wei Q, Ding Y, Zhang J, Zhao Y, Zhou Q*. CT45A1 acts as a new proto-oncogene to trigger tumorigenesis and cancer metastasis. Cell Death Dis 2014;5:e1285

31.   †Shen B#, Shang Z#, Wang B#, Zhang L#, Zhou F#, Li T, Chu M, Jiang H, Wang Y, Qiao T, Zhang J, Sun W, Kong X, He Y*. Genetic dissection of tie pathway in mouse lymphatic maturation and valve development. Arterioscler Thromb Vasc Biol 2014;34:1221-30.

32.   †Shi M#, Zhou X#, Zhang Z, Wang M, Chen G, Han K, Cao B, Liu Z, Mao X*. A novel PI3K inhibitor displays potent preclinical activity against an androgen-independent and PTEN-deficient prostate cancer model established from the cell line PC3. Toxicol Lett 2014;228:133-9.

33.   †Song H#, Huang L#, Zhang M, Wang X, Song S, Yang L*. Transphosphorylation of EGFR at Y845 plays an important role in its autophosphorylation and kinase activity. Oncol Rep 2014;31:2393-8.

34.   †Sun S#, Liu Z#, Zhou H#, Li G, Liu M, Yao J, Zhou T, An G, Wu Q*, Dong N*. The Role of fucosylation in the promotion of endothelial progenitor cells in neovascularization and bone repair. Biomaterials 2014;35:3777-85.

35.   Tan Y, Qin S, Hou X, Qian X, Xia J, Li Y, Wang R, Chen C, Yang Q, Miele L, Wu Q*, Wang Z*. Proteomic-based analysis for identification of proteins involved in 5-fluorouracil resistance in hepatocellular carcinoma. Curr Pharm Des 2014;20:81-7.

36.   †Tang X#, Song YH#, Sun A, Ruan C, Wu D*. Successful treatment of relapsed acute myeloid leukemia without chemotherapy. J Clin Oncol 2014 Apr 7. [Epub ahead of print]

37.   Vandergriff AC#, Hensley TM#, Henry ET#, Shen D, Anthony S, Zhang J, Cheng K*. Magnetic targeting of cardiosphere-derived stem cells with ferumoxytol nanoparticles for treating rats with myocardial infarction. Biomaterials 2014;35:8528-39.

38.   †Wang H#, Jiang X#, Wang X#, Wei X, Zhu Y, Sun B, Su Y, He S*, He Y*. Hairpin DNA-assisted silicon/silver based surface enhanced Raman scattering platform for ultrahighly sensitive and specific discrimination of deafness mutations in a real system. Anal Chem 2014;86:7368-76.

39.   †Wang L#, Ye X#, Liu Y, Wei W*, Wang Z*. Aberrant regulation of Fbw7 in cancer. Oncotarget 2014;5:2000-15.

40.   Wang R#, Cheng L#, Xia J, Wang Z, Wu Q*, Wang Z*. Gemcitabine resistance is associated with epithelial-mesenchymal transition and induction of HIF-1α in pancreatic cancer cells. Curr Cancer Drug Targets 2014;14:407-17.

41.   †Wang X#, Li Y#, Liu S#, Yu X#, Li L, Shi C, He W, Li J, Xu L, Hu Z, Yu L, Yang Z, Chen Q, Ge L, Zhang Z, Zhou B, Jiang X, Chen S, He S*. Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense. Proc Natl Acad Sci USA 2014;111:15438-43.

42.   Wang Y#*, Gu X#, Zhang G#, Wang L, Wang T, Zhao Y, Zhang X, Zhou Y, Kadin M, Tu P*. SATB1 overexpression promotes malignant T-cell proliferation in cutaneous CD30+ lymphoproliferative disease by repressing p21. Blood 2014;123:3452-61.

43.   †Wang Z#, Xu F#, Yuan N#, Niu Y, Liu W, Cao Y, Cai J, Song L, Li X, Fang Y, Zhao W, Hu S, Chen S, Zhang S*, Wang J*. Rapamycin inhibits pre-B acute lymphoblastic leukemia cells by downregulating DNA and RNA polymerases. Leuk Res 2014;38:940-7.

44.   Wang Z#, Liu P#, Inuzuka H, Wei W*. Roles of F-box proteins in cancer. Nat Rev Cancer 2014;14:233-47.

45.   †Wang Z, Wei W*. Fbxo45 joins the ‘Par-4’ty in controlling apoptosis of cancer cells. Cell Death Differ 2014;21:1508-10.

46.   Xia J#, Cheng L#, Mei C, Ma J, Shi Y, Zeng F, Wang Z*, Wang Z*. Genistein inhibits cell growth and invasion through regulation of MiR-27a in pancreatic cancer cells. Curr Pharm Des 2014;20:5348-53.

47.   †Xie Z, Dai J, Yang A, Wu Y*. A role for bradykinin in the development of anti-collagen antibody-induced arthritis. Rheumatology (Oxford) 2014;53:1301-6.

48.   †Xing S#, Shen C#, Godard MP#, Wang J, Yue Y, Yang S, Zhao Q, Zhang S, Wang T, Yang X, Delafontaine P, He Y*, Song YH*. Bortezomib inhibits C2C12 growth by inducing cell cycle arrest and apoptosis. Biochem Biophys Res Commun 2014;445:375-80.

49.   †Xu X#, Zhang J#, Han K, Zhang Z, Chen G, Zhang J, Mao X*, Cao B*. Natural pesticide dihydrorotenone arrests human plasma cancer cells at the G0/G1 phase of the cell cycle. J Biochem Mol Toxicol 2014;28:232-8.

50.   †Yang A, Dai J, Xie Z, Colman RW, Wu Q, Birge RB, Wu Y*. High molecular weight kininogen binds phosphatidylserine and opsonizes urokinase plasminogen activator receptor-mediated efferocytosis. J Immunol 2014;192:4398-408.

51.   Yang Q#, Zhang F#, Ding Y, Huang J, Chen S, Wu Q, Wang Z, Wang Z*, Chen C*. Antitumour activity of the recombination polypeptide GST-NT21MP is mediated by inhibition of CXCR4 pathway in breast cancer. Br J Cancer 2014;110:1288-97.

52.   Yang Q#, Huang J#, Wu Q, Cai Y, Zhu L, Lu X, Chen S, Chen C*, Wang Z*. Acquisition of epithelial-mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells. Br J Cancer 2014;110:1958-67.

53.   Yang Q#, Jia C#, Wang P, Xiong M, Cui J, Li L, Wang W, Wu Q, Chen Y*, Zhang T*. MicroRNA-505 identified from patients with essential hypertension impairs endothelial cell migration and tube formation. Int J Cardiol 2014;177:925-34.

54.   †Ye X#, Wang L#, Shang B, Wang Z*, Wei W*. NEDD4: A Promising Target for Cancer Therapy. Curr Cancer Drug Targets 2014;14:549-56.

55.   †Yi W#, Li Q#, Shen J#, Ren L, Liu X, Wang Q, He S, Wu Q, Hu H, Mao X*, Zhu L*. Modulation of platelet activation and thrombus formation using a pan-PI3K inhibitor S14161. PLoS One 2014;9:e102394.

56.   †Yu D#, Fu S#, Cao Z#, Bao M, Zhang G, Pan Y, Liu W, Zhou Q*. Unraveling the novel anti-osteosarcoma function of coptisine and its mechanisms. Toxicol Lett 2014;226:328-36.

57.   Yuan L, Sun L, Yang L, Jing Y*. Acute graft-versus-host disease in a nonhematopoietic stem cell transplantation candidate treated with decitabine followed by granulocyte colony-stimulating factor–primed peripheral blood stem cells infusion: a special entity of the disease? Transfusion 2014;54:190-3.

58.   †Yue Y#, Wang Y#, He Y#, Yang S, Chen Z, Wang Y, Xing S, Shen C, Amin HM, Wu D*, Song YH*. Reversal of bortezomib resistance in myelodysplastic syndrome cells by MAPK inhibitors. PLoS One. 2014;9:e90992.

59.   †Zhang S#*, Wang W#, Gu Q, Xue J, Cao H, Tang Y, Xu X, Cao J*, Zhou J, Wu J, Ding WQ. Protein and miRNA profiling of radiation-induced skin injury in rats: the protective role of peroxiredoxin-6 against ionizing radiation. Free Radic Biol Med 2014;69:96-107.

60.   †Zhang S#*, Wang W#, Peng Y, Gu Q, Luo J, Zhou J, Wu J, Hou Y, Cao J. Amelioration of radiation-induced skin injury by HIV-TAT-mediated protein transduction of RP-1 from Rana pleurade. Int J Med Sci 2014;11:44-51.

61.   Zhang Y#, Lu Y#, Ma L, Cao X, Xiao J, Chen J, Jiao S, Gao Y, Liu C, Duan Z, Li D, He Y, Wei B*, Wang H*. Activation of vascular endothelial growth factor receptor-3 in mcrophages restrains TLR4-NF-κB signaling and protects against endotoxin shock. Immunity 2014;40:501-14.

62.   †Zhang Y#*, Yang W#, Zhu H, Qian Y, Zhou L, Ren Y, Ren X, Zhang L, Liu X, Liu C, Ming Z, Li B, Chen B, Wang J, Liu Y, Yang J*. Regulation of autophagy by miR-30d impacts sensitivity of anaplastic thyroid carcinoma to cisplatin. Biochem Pharmacol 2014;87:562-70.

63.   †Zhang Y#, Li H#, Zhou J, Wang A, Yang J, Wang C, Liu M, Zhou T, Zhu L, Zhang Y, Dong N*, Wu Q*. A corin variant identified in hypertensive patients that alters cytoplasmic tail and reduces cell surface expression and activity. Sci Rep 2014;4:7378.

64.   †Zhao L#, Mei Y#, Sun Q#, Guo L, Wu Y, Yu X, Hu B, Liu X*, Liu H*.Autologous tumor vaccine modified with recombinant new castle disease virus expressing IL-7 promotes antitumor immune response. J Immunol 2014;193:735-45.

65.   †Zhao W#, Wei L#, Tan D, Su G, Zheng Y, He C, Mao Z, Singleton TP, Yin B*. Cellular intrinsic mechanism affecting the outcome of AML treated with Ara-C in a syngeneic mouse model. PLoS One 2014;9:e109198.

66.   †Zheng Y#, Tan D#, Chen Z, Hu C, Mao ZJ, Singleton TP, Zeng Y, Shao X, Yin B*. A non-genetic approach to labelling acute myeloid leukemia and bone marrow cells with quantum dots. J Nanosci Nanotechnol 2014;14:4014-21.

67.   †Zhou H#, Ge Y#, Sun L#, Ma W, Wu J, Zhang X, Hu X, Eaves CJ, Wu D*, Zhao Y*. Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth. PLoS One 2014;9:e86195.

68.   †Zhou J, Wu Y*, Wang L, Rauova L, Hayes VM, Poncz M, Essex DW*. The disulfide isomerase ERp57 is required for fibrin deposition in vivo. J Thromb Haemost 2014;12:1890-7.

69.   †Zhou Y, Wu Q*. Corin in natriuretic peptide processing and hypertension. Curr Hypertens Rep 2014;16:415.

70.   †Zuo Y, Yang J*, He J, Zhao Y, He Y. An uncoordinated-5 homolog B receptor monoclonal antibody regulates A375 melanoma cell migration. Monoclon Antib Immunodiagn Immunother 2014;33:280-6.

71.   †Zou Y, Song Y, Yang W, Meng F*, Liu H, Zhong Z*. Galactose-installed photo-crosslinked pH-sensitive degradable micelles for active targeting chemotherapy of hepatocellular carcinoma in mice. J Control Release 2014;193:154-61.

72.   †Zhu J, Pan P, Li Y, Wang M, Li D, Cao B, Mao X*, Hou T*. Theoretical studies on beta and delta isoform-specific binding mechanisms of phosphoinositide 3-kinase inhibitors. Mol Biosyst 2014;10:454-66.

73.   †Zhu X#, Zheng X#, Wu Y*. Cleaved high molecular weight kininogen stimulates JNK/FOXO4/MnSOD pathway for induction of endothelial progenitor cell senescence. Biochem Biophys Res Commun 2014;450:1261-5.