†with Suda as the first affiliation; #co-first authors; *corresponding author

1.    Andrade JN#, Tang J#, Hensley MT, Vandergriff A, Cores J, Henry E, Allen TA, Caranasos TG, Wang Z, Zhang T, Zhang J*, Cheng K*. Rapid and efficient production of coronary artery ligation and myocardial infarction in mice using surgical clips. PLoS One 2015;10:e0143221.

2.    †Cao Y#,*, Cai J#, Li X#, Yuan N, Zhang S*. Autophagy governs erythroid differentiation both in vitro and in vivo. Hematology 2015 Jun 29. [Epub ahead of print]

3.    †Cao Y, Cai J, Zhang S, Yuan N, Fang Y, Wang Z, Li X, Cao D, Xu F, Lin W, Song L, Wang Z, Wang J, Xu X, Zhang Y, Zhao W, Hu S, Zhang X, Wang J*. Autophagy sustains hematopoiesis through targeting notch. Stem Cells Dev 2015;24:2660-73.

4.    †Cao Y, Cai J, Zhang S, Yuan N, Li X, Fang Y, Song L, Shang M, Liu S, Zhao W, Hu S, Wang J*. Loss of autophagy leads to failure in megakaryopoiesis, megakaryocyte differentiation and thrombopoiesis in mice. Exp Hematol 2015;43:488-94.

5.    †Cao Y#, Zhang A#, Cai J, Yuan N, Lin W, Liu S, Xu F, Song L, Li X, Fang Y, Wang Z, Wang Z, Wang J, Zhang H, Zhao W, Hu S, Zhang S*, Wang J*. Autophagy regulates the cell cycle of murine HSPCs in a nutrient-dependent manner. Exp Hematol 2015;43:229-42.

6.    †Cao Y, Zhang S, Yuan N, Wang J, Li X, Xu F, Lin W, Song L, Fang Y, Wang Z, Wang Z, Zhang H, Zhang Y, Zhao W, Hu S, Zhang X, Wang J*. Hierarchal autophagic divergence of hematopoietic system. J Biol Chem 2015;290:23050-63.

7.    Chen S, Cao P, Dong N, Peng J, Zhang C, Wang H, Zhou T, Yang J, Zhang Y, Martelli EE, Naga Prasad SV, Miller RE, Malfait AM, Zhou Y, Wu Q*. PCSK6-mediated corin activation is essential for normal blood pressure. Nat Med 2015;21:1048-53.

8.    †Chen Y, Zhao Y, Cheng Q, Wu D, Liu H*. The role of intestinal microbiota in acute graft-versus-host disease. J Immunol Res 2015;2015:145859.

9.    †Cheng Q, Ma S, Lin D, Mei Y, Gong H, Lei L, Chen Y, Zhao Y, Hu B, Wu Y, Yu X, Zhao L, Liu H*. The S1P1 receptor-selective agonist CYM-5442 reduces the severity of acute GVHD by inhibiting macrophage recruitment. Cell Mol Immunol 2015;12:681-91.

10.   †Dong T, Cheng Y, Yang F, Sun P, Zhu CJ, Zhu L*, Zhang G*. Chronic stress facilitates the development of deep venous thrombosis. Oxid Med Cell Longev 2015;2015:384535.

11.   Dong T#, Li C#, Wang X, Dian L, Zhang X, Li L, Chen S, Cao R, Li L, Huang N, He S*, Lei X*. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nat Commun 2015;6:6522. 

12.   †Dong Y#, Li K#, Xu Z, Ma H, Zheng J, Hu Z, He S, Wu Y, Sun Z, Luo L*, Li J, Zhang H*, Zhang X*. Exploration of the linkage elements of porcupine antagonists led to potent Wnt signaling pathway inhibitors. Bioorg Med Chem 2015;23:6855-68.

13.   Gao J#, Wang L, Long B, Ye X, Su J, Yin X, Zhou X*, Wang Z*. Arsenic trioxide inhibits cell growth and invasion via down-regulation of Skp2 in pancreatic cancer cells. Asian Pac J Cancer Prev 2015;16: 3805-10.

14.   Gong Y#, Lin M#, Piao L, Li X, Yang F, Zhang J, Xiao B, Zhang Q, Song WL, Yin H, Zhu L, Funk CD, Yu Y*. Aspirin enhances protective effect of fish oil against thrombosis and injury-induced vascular remodelling. Br J Pharmacol 2015;172:5647-60.

15.   Hensley MT#, de Andrade J#, Keene B#, Meurs K#, Tang J, Wang Z, Caranasos TG, Piedrahita J, Li TS, Cheng K*. Cardiac regenerative potential of cardiosphere-derived cells from adult dog hearts. J Cell Mol Med 2015;19:1805-13.

16.   †Huang Y, Carbone DP*. Mechanisms of and strategies for overcoming resistance to anti-vascular endothelial growth factor therapy in non-small cell lung cancer. Biochim Biophys Acta 2015;1855:193-201.

17.   Jiang W#, Huang Y#, An Y, Kim BY*. Remodeling tumor vasculature to enhance delivery of intermediate-sized nanoparticles. ACS Nano 2015;9:8689-96.

18.   †Li H#, Zhang Y#, Wang L, Dong N, Qi X, Wu Q*. A novel cytoplasmic tail motif regulates mouse corin expression on the cell surface. Biochem Biophys Res Commun 2015;465:152-8.

19.   †Lin D, Lei L, Zhang Y, Hu B, Bao G, Liu Y, Song Y, Liu C, Wu Y, Zhao L, Yu X, Liu H*. Secreted IL-1α promotes T-cell activation and expansion of CD11b(+) Gr1(+) cells in carbon tetrachloride-induced liver injury in mice. Eur J Immunol 2015;45:2084-98.

20.   †Lin W#, Yuan N#, Wang Z, Cao Y, Fang Y, Li X, Xu F, Song L, Wang J, Zhang H, Yan L, Xu L, Zhang X, Zhang S*, Wang J*. Autophagy confers DNA damage repair pathways to protect the hematopoietic system from nuclear radiation injury. Sci Rep 2015;5:12362.

21.   Liu J#, Shaik S#, Dai X, Wu Q, Zhou X, Wang Z*, Wei W*. Targeting the ubiquitin pathway for cancer treatment. Biochim Biophys Acta 2015;1855:50-60.

22.   †Liu W#, Meng M#, Zhang B, Du L, Pan Y, Yang P, Gu Z, Zhou Q*, Cao Z*. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity. Toxicol Appl Pharmacol 2015;287:98-110.

23.   †Liu Y#, Wu Y#, Wang Y, Cai Y, Hu B, Bao G, Fang H, Zhao L, Ma S, Cheng Q, Song Y, Liu Y, Zhu Z, Chang H, Yu X, Sun A, Zhang Y, Vignali DA, Wu D*, Liu H*. IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects. Leukemia 2015;29:939-46. 

24.   †Ma J, Fang B, Zeng F, Ma C, Pang H, Cheng L, Shi Y, Wang H, Yin B*, Xia J*, Wang Z*. Down-regulation of miR-223 reverses epithelial-mesenchymal transition in gemcitabine-resistant pancreatic cancer cells. Oncotarget 2015;6:1740-9. 

25.   †Ma W#, Liu J#, Xie J#, Zhang X, Zhou H, Yao H, Zhang W, Guo D, Zhu L, Xiao L, Wu D, Xu H, Chen S*, Zhao Y*. Modulating the growth and imatinib sensitivity of chronic myeloid leukemia stem/progenitor cells with pullulan/microRNA anoparticles in vitro. J Biomed Nanotechnol 2015;11:1961-74.

26.   †Qi L#, Sun X#, Li F, Zhu B, Braun FK, Liu Z, Tang J, Wu C, Xu F, Wang H, Velasquez LA, Zhao K, Lei F, Zhang J, Shen Y, Zou J, Meng H, An G, Yang L*, Zhang X*. HMGB1 promotes mitochondrial dysfunction-triggered striatal neurodegeneration via autophagy and apoptosis activation. PLoS One 2015;10:e0142901.

27.   Qiao Y, Guo D, Meng L, Liu Q, Liu X, Tang C, Yi G, Wang Z, Yin W, Tian G, Yuan Z*. Oxidized low density lipoprotein accumulates cholesterol esters via the PKCα adipophilin ACAT1 pathway in RAW264.7 cells. Mol Med Rep 2015;12:3599-606.

28.   †Shen L, Xie Y, Qian X, Zhuang Z, Jiao Y, Qi X*. A single nucleotide polymorphism in the promoter region of let-7 family is associated with lung cancer risk in Chinese. Genet Mol Res 2015;14:4505-12.

29.   Singleton TP, Yin B, Teferra A, Mao JZ*. Spectrum of clonal large granular lymphocytes (LGLs) of αβ T Cells: T-Cell clones of undetermined significance, T-Cell LGL leukemias, and T-Cell immunoclones. Am J Clin Pathol 2015;144:137-44.

30.   Song W, Wang H, Wu Q*. Atrial natriuretic peptide in cardiovascular biology and disease (NPPA). Gene 2015;569:1-6.

31.   †Su G#, Lian X#, Tan D, Tao H, Liu H, Chen S, Yin H, Wu D, Yin B*. Aberrant expression of ecotropic viral integration site-1 in acute myeloid leukemia and acute lymphoblastic leukemia. Leuk Lymphoma 2015;56:472-9.

32.   †Su J#, Yin X#, Zhou X, Wei W*, Wang Z*. The functions of F-box proteins in regulating the epithelial to mesenchymal transition. Curr Pharm Des 2015;21:1311-7.

33.   †Sun L#, Zhou H#, Liu H#, Ge Y, Zhang X, Ma W, Wu D*, Zhao Y*. GAS2-Calpain2 axis contributes to the growth of leukemic cells. Acta Biochim Biophys Sin (Shanghai) 2015;47:795-804.

34.   Vandergriff AC, de Andrade JB, Tang J, Hensley MT, Piedrahita JA, Caranasos TG, Cheng K*. Intravenous cardiac stem cell-derived exosomes ameliorate cardiac dysfunction in doxorubicin induced dilated cardiomyopathy. Stem Cells Int 2015;2015:960926.

35.   Vandergriff AC, Hensley M, Cheng K*. Isolation and cryopreservation of neonatal rat cardiomyocytes. J Vis Exp 2015 Apr 9;(98).

36.   Vishwamitra D, Curry CV, Alkan S, Song YH, Gallick GE, Kaseb AO, Shi P, Amin HM*. The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK+ T-cell lymphoma. Mol Cancer 2015;14:53.

37.   Wang H, Zhou T, Peng J, Xu P, Dong N, Chen S, Wu Q*. Distinct roles of n-glycosylation at different sites of corin in cell membrane targeting and ectodomain shedding. J Biol Chem 2015;290:1654-63.

38.   †Wang L#, Zhang J#, Wan L#, Zhou X, Wang Z*, Wei W*. Targeting Cdc20 as a novel cancer therapeutic strategy. Pharmacol Ther 2015;151:141-51.

39.   †Wang L#, Ye X#, Cai X, Su J, Ma R, Yin X, Zhou X, Li H*, Wang Z*. Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells. Oncotarget 2015;6:18027-37.

40.   Wang R, Li Y, Hou Y, Yang Q, Chen S, Wang X, Wang Z, Yang Y, Chen C, Wang Z*, Wu Q*. The PDGF-D/miR-106a/Twist1 pathway orchestrates epithelial-mesenchymal transition in gemcitabine resistance hepatoma cells. Oncotarget 2015;6:7000-10

41.   †Wang Z*. Targeting epithelial-to-mesenchymal transition for cancer therapy. Curr Pharm Des 2015;21:1239.

42.   †Wang Z#, *, Dai X#, Zhong J#, Inuzuka H, Wan L, Li X, Wang L, Ye X, Sun L, Gao D, Zou L, Wei W*. SCF/beta-TRCP promotes cell growth by targeting PR-Set7/Set8 for degradation. Nat Commun 2015;6:10185.

43.   Wang Z#, Yang J#,*, Zhu Y, Zhu Y, Zhang B, Zhou Y. Differential expression of 2IgB7-H3 and 4IgB7-H3 in cancer cell lines and glioma tissues. Oncol Let 2015;10:2204-8.

44.   †Wu H, Deng J, Zheng J, You Y, Li N, Li W, Wu D, Zhou Y*. Functional polymorphisms in the CD44 gene and acute myeloid leukemia cancer risk in a Chinese population. Mol Carcinog 2015;54:102-10.

45.   †Wu Y, Ma S, Liu Y, Lei L, Hu B, Liu H*. The dynamic impact of hydrodynamic gene transfer on the immune system. Int J Clin Exp Med 2015;8:8540-50.

46.   †Xu Z#, Li J#, Wu Y, Sun Z, Luo L*, Hu Z, He S, Zheng J*, Zhang H, Zhang X*. Design, synthesis, and evaluation of potent Wnt signaling inhibitors featuring a fused 3-ring system. Eur J Med Chem 2015;108:154-65.

47.   †Yang P#, Huo Z#, Liao H#, Zhou Q*. Cancer/testis antigens trigger epithelial-mesenchymal transition and genesis of cancer stem-like cells. Curr Pharm Des 2015;21:1292-300.

48.   †Yang P#, Fu S#, Cao Z, Liao H, Huo Z, Pan Y, Zhang G, Gao A, Zhou Q*. Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy. Toxicol Appl Pharmacol 2015;288:269-79.

49.   Yang Q#, Wang Y#, Lu X#, Zhao Z, Zhu L, Chen S, Wu Q, Chen C*, Wang Z*. MiR-125b regulates epithelial-mesenchymal transition via targeting Sema4C in paclitaxel-resistant breast cancer cells. Oncotarget 2015;6:3268-79.

50.   †Yao H, Pan J, Wu C, Shen H, Xie J, Wang Q, Wen L, Wang Q, Ma L, Wu L, Ping N, Zhao Y, Sun A*, Chen S*. Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22). Mol Cancer 2015;14:81.

51.   †Yin J#, Xie X#, Zhang F#, Chen Z, Hu C, Su G, Liu H, Zheng Y, He C, Shen H, Qiu Q, He J, Pan Z, Gale RP, Wu D, Yin B*. Low frequency of mutations in Chinese with acute myeloid leukemia: Different disease or different aetiology? Leuk Res 2015;39:646-8.

52.   †Yin X#, Su J#, Zhou X, Guo J, Wei W*, Wang Z*. K-ras-driven engineered mouse models for pancreatic cancer. Discov Med 2015;19:15-21.

53.   †Yu X, Li Y, Chen Q, Su C, Zhang Z, Yang C, Hu Z, Hou J, Zhou J, Gong L, Jiang X, Zheng C*, He S*. Herpes simplex virus Type 1 (HSV-1) and HSV-2 mediate species specific modulations of programmed necrosis through the viral ribonucleotide reductase large subunit R1. J Virol 2015 Nov 11. pii: JVI.02446-15.

54.   †Yuan N#, Song L#, Lin W, Cao Y, Xu F, Liu S, Zhang A, Wang Z, Li X, Fang Y, Zhang H, Zhao W. Hu S, Wang J*, Zhang S*. Autophagy collaborates with ubiquitination to downregulate oncoprotein E2A/Pbx1 in B-cell acute lymphoblastic leukemia. Blood Cancer J 2015;5:e274.

55.   †Yuan N, Song L, Zhang S, Lin W, Cao Y, Xu F, Fang Y, Wang Z, Zhang H, Li X, Wang Z, Cai J, Wang J, Zhang Y, Mao X, Zhao W, Hu S, Chen S, Wang J*. Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia. Haematologica 2015;100:345-56.

56.   †Zeng Z, Inoue K, Sun H, Leng T, Feng X, Zhu L*, Xiong Z*. TRPM7 regulates vascular endothelial cell adhesion and tube formation. Am J Physiol Cell Physiol 2015;308:C308-18.

57.   †Zeng Z, Leng T, Feng X, Sun H, Inoue K, Zhu L*, Xiong Z*. Silencing TRPM7 in mouse cortical astrocytes impairs cell proliferation and migration via ERK and JNK signaling pathways. PLoS One 2015;10:e0119912.

58.   †Zhang X#, Ma W#, Cui J#, Yao H, Zhou H, Ge Y, Xiao L, Hu X, Liu BH, Yang J, Li YY, Chen S, Eaves CJ, Wu D*, Zhao Y*. Regulation of p21 by TWIST2 contributes to its tumor-suppressor function in human acute myeloid leukemia. Oncogene 2015;34:3000-10.

59.   †Zhang L, Jiang G*, Yao F, Liang G, Wang F, Xu H, Wu Y, Yu X, Liu H*. Osthole promotes anti-tumor immune responses in tumor-bearing mice with hepatocellular carcinoma. Immunopharmacol Immunotoxicol 2015;37:301-7.

60.   Zhang Y#, Sun M#, Shi W, Yang Q, Chen C, Wang Z*, Zhou X*. Arsenic trioxide suppresses transcription of hTERT through down-regulation of multiple transcription factors in HL-60 leukemia cells. Toxicol Lett 2015;232:481-9.

61.   †Zhao Q#, Yang S#, Wang J#, Zhou J, Xing S, Shen C, Wang X, Yue Y, Song J, Chen M, Wei Y, Zhou Q, Dai T, Song YH*. TNF alpha inhibits myogenic differentiation of C2C12 cells through NF-κB activation and impairment of IGF-1 signaling pathway. Biochem Biophys Res Commun 2015;458:790-5.

62.   †Zhao Y#, Zhu M#, Jiang M#, Zuo B, Wu Q, Ruan C, He Y*. An improved flow cytometric immunobead array to detect autoantibodies in plasma from patients with immune thrombocytopenic purpura. Clin Chim Acta 2015;438:396-400.

63.   Zheng H#, Ma R#, Wang Q, Zhang P, Li D, Wang Q, Wang J, Li H*, Liu H*, Wang Z*. MiR-625-3p promotes cell migration and invasion via inhibition of SCAI in colorectal carcinoma cells. Oncotarget 2015;6:27805-15.

64.   †Zhou J#, Wu Y#,*, Wang L, Rauova L, Hayes VH, Poncz M, Essex DW*. The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis. J Clin Invest 2015;125:4391-406.

65.   †Zong Y#, He S#, Chu F, Jing Y, Hunsucker SA, Yang T, You F, Ye S, Li Y, Tang J, Meng H, An G, Zhang X, Zhang B, Yang L*. Identification of co-inhibitory receptors PD-1 and TIM-3 on T cells from gastric cancer patients. Cell Mol Biol Accepted on Dec 4, 2015 (in press)

66.   †Zou J, Chen D, Zong Y, Ye S, Tang J, Meng H, An G, Zhang X, Yang L*. Immunotherapy based on bispecific T-cell engager with hIgG1 Fc sequence as a new therapeutic strategy in multiple myeloma. Cancer Sci 2015;106:512-21.