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Principal Investigators
Associate Professor, PhD supervisor
1.Post transcription modification in "Reprogramming" and "rewiring" of tumor metabolic pathways.
2.Metabolites as signal molecules participate in the regulation of signal transduction pathways.
3.The relationship of special "tumor metabolites" and oncogene in leukemia.
Wei Deng, Ph.D.
The structure and interaction of several important platelet membrane receptors including GPIb, GPVI, ADAM17/10, thrombin receptors and ADP receptors
Kesheng Dai, Ph.D.
The roles of platelets in thrombosis, hemostasis, and other major diseases.
研究员 博士生导师
1
副教授,硕士生导师
血液衰老与非医疗干预
Yuhui Huang, Ph.D.
tumor microenvironment
Yulong He, Ph.D., Professor
Regulation of lymphatic and blood vascular network formation, remodeling, and valve development
Mechanism of tumor lymphangiogenesis, angiogenesis and metastasis
Metabolic regulation in vascular diseases and regeneration
Associate Research Fellow
血流动力学诱导内皮表型转变及对动脉粥样硬化斑块的调控
副教授,硕士生导师
血细胞对凝血系统的调控机制
新型凝血功能检测法的开发和应用
Jiangrong Wang, Ph.D.
Blood aging and manufacturing
Qingyu Wu, M.D., Ph.D.
Role of cardiovascular proteases in regulating vascular and cardiac function
Yi Wu, M.D., Ph.D.
Molecular and cellular mechanisms of thrombosis
Role of plasma kallikrein-kinin system in thrombosis, vascular biology and inflammation
Recognition and uptake of apoptotic cells in innate immunity
Professor, PhD supervisor
1)Identify novel regulators in erythropoiesis/hematopoiesis by systematic and integrated strategies including CRISPR/Cas9 mediated gene editing and high-throughput genetic screening, transcriptome and proteomics;
2)Target therapy for AML and MDS by identifying novel druggable targets;
3)Genetics and molecular mechanism in thalassemia and HSC based gene editing.
Professor, PhD supervisor
Identification of novel ion channels and their in vivo functions.
Gene therapy of cardiac ion channelopathy.
ATP-sensitive potassium channel in cardioprotection.
Lin Yang, Ph.D.
Immune cell therapy
CAR-T cell therapy
Study of the antitumor mechanism of γδ T cells
Translational medicine research in immuno-oncology
副研究员,硕士生导师
急性B细胞淋系白血病治疗研究
Beclin1的非经典功能在造血调控中的作用与机制研究
造血系统对神经系统和骨骼系统的跨系统调控机制研究
Liming Yu, Ph.D. Professor
Dissect the inter-organ crosstalk mechanisms linking hepatic dyslipidemia to myocardial dysfunction.
Define CHIP-driven inflammatory mechanisms?in atherosclerosis.
Develop novel lineage-tracing mice?to study cellular clonal expansion.
副教授,硕士生导师
靶向白血病干细胞:聚焦于自我更新相关关键基因的功能鉴定,旨在发现可干预的新治疗靶点,以根除疾病源头。
克服临床耐药:系统探究白血病耐药产生的分子机制,并以此为基础,探索优化现有治疗方案的策略。
Yun Zhao, Ph.D.
Identification of the critical genes in the initiation and progression of chronic myeloid leukemia (CML)
副研究员,硕士研究生
血栓形成的细胞与分子机制研究